[2H9]-4-Carboxy Tolbutamide
4-Carboxy Tolbutamide-d9
CAS: 1184973-50-9
Molecular Formula: C12H16N2O5S
[2H9]-4-Carboxy Tolbutamide - Names and Identifiers
[2H9]-4-Carboxy Tolbutamide - Physico-chemical Properties
| Molecular Formula | C12H16N2O5S |
| Molar Mass | 300.33084 |
| Melting Point | >3000C (dec) |
| Solubility | DMSO (Slightly), Methanol (Slightly), Water (Slightly) |
| Appearance | Solid |
| Color | White to Off-White |
| Storage Condition | Hygroscopic, -20°C Freezer, Under Inert Atmosphere |
| Stability | Hygroscopic |
[2H9]-4-Carboxy Tolbutamide - Introduction
4-Carboxy Tolbutamide-d9 is a 4-Carboxy Tolbutamide compound with deuterium (d9). The following is an introduction to its nature, use, preparation and safety information:
Nature:
-Appearance: White or off-white crystalline powder
-molecular formula: C12D9NO4S
-Molecular weight: 273.41g/mol
-Melting point: 139-141 degrees Celsius
-Solubility: insoluble in water, soluble in chloroform or ether
Use:
4-Carboxy Tolbutamide-d9 is a drug metabolite, which is commonly used in pharmacokinetic studies and drug stable isotope labeling analysis. It can be used as an internal standard or standard substance in drug metabolism and pharmacokinetic studies.
Method:
A common method for the preparation of 4-carboxyxy Tolbutamide-d9 is obtained by deuteration of the synthetic intermediate of 4-carboxytobutamide. The deuteration reaction generally involves performing a hydrogen source exchange reaction on the compound, using a deuterating reagent such as sodium deuteride (NaD) or deuteric acid (D2O) to replace a hydrogen atom of a hydroxyl group or other dehydrogenatable moiety.
Safety Information:
Since the 4-Carboxy Tolbutamide-d9 is mainly used for scientific research purposes, there are fewer opportunities for ordinary personnel to contact it. However, as with most chemical substances, appropriate safety precautions, such as gloves and lab clothes, should be taken when exposed to avoid inhalation, ingestion or direct contact with skin and eyes. In the use of the process should also pay attention to comply with the laboratory safety procedures. In case of accidental contact or ingestion, medical help should be sought immediately.
Nature:
-Appearance: White or off-white crystalline powder
-molecular formula: C12D9NO4S
-Molecular weight: 273.41g/mol
-Melting point: 139-141 degrees Celsius
-Solubility: insoluble in water, soluble in chloroform or ether
Use:
4-Carboxy Tolbutamide-d9 is a drug metabolite, which is commonly used in pharmacokinetic studies and drug stable isotope labeling analysis. It can be used as an internal standard or standard substance in drug metabolism and pharmacokinetic studies.
Method:
A common method for the preparation of 4-carboxyxy Tolbutamide-d9 is obtained by deuteration of the synthetic intermediate of 4-carboxytobutamide. The deuteration reaction generally involves performing a hydrogen source exchange reaction on the compound, using a deuterating reagent such as sodium deuteride (NaD) or deuteric acid (D2O) to replace a hydrogen atom of a hydroxyl group or other dehydrogenatable moiety.
Safety Information:
Since the 4-Carboxy Tolbutamide-d9 is mainly used for scientific research purposes, there are fewer opportunities for ordinary personnel to contact it. However, as with most chemical substances, appropriate safety precautions, such as gloves and lab clothes, should be taken when exposed to avoid inhalation, ingestion or direct contact with skin and eyes. In the use of the process should also pay attention to comply with the laboratory safety procedures. In case of accidental contact or ingestion, medical help should be sought immediately.
Last Update：2024-04-09 21:04:16
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CAS: 1184973-50-9
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CAS: 1184973-50-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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